Protein Details: Glutamate receptor 1.4

Protein ID

ICDB_Pro_1274

Protein Name

Glutamate receptor 1.4

Gene Name

GLR1.4; At3g07520; F21O3.23

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

861 amino acids

AlphaFoldDB

AF-Q8LGN1-F1-model_v4.pdb

Function

Glutamate-gated receptor that probably acts as a non-selective cation channel. Can transport calcium ions. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.

Sequence

MENCMIRNTGYFLTIFFLAFISFAVTCSGTNQKDNVDRLPVVYEDVRIGLVVDMGSMEGKLVTTSISMALSDFYHVNNGYRTRVSVLSRDSHGDPLQALAAAMDLLQTEQVEALVGGQSLLEAKNLAELGEKTKVPVISSFQVPSSLSLAKYNYFIQATHDTSSEAKGIAALFSNFDWRTAVLIYEDDDDWRESIQPLVGHFQQNAIHIEYKAEFSVSSNEECIMKQLRKFKASGIRIFVAHISERIANRLFPCARRLGMMEEGYAWILTARSMNNFQDTNYLAKEEMEGVIGFKSYIPLTEELHNFTLRWKRSLRLEEVVTRMSVCSIWAHDIAWSLARAAEVAKLPGLSVYDLLEAIPESAKHKGLSGDIKFIDKKFISDKFEIVNMIGRGERSVGLWNSGSFISNRRRRLSSTKALETIIWPGGSTRIPKIRSLKEKRHGKKKKLRVLVPAGNITPQILEVKTDFKTGVTAATGYCIDVFETSILPFNYEVEYIPWPGAINYKNYNDLVYTLYSQKDKYDAAVGDITITDNRSLYVDFTLPFTDMGLAVVTAKDKSMWIIFKPLTLSLWLTIASFFILTGAIVWLIERHDNADFQGSCFQQIGTLLCFGFSTLVFAHRERLQHNMSRFVVIVWIFAVLILTSNYTATLTSVMTVQQIRGLKSNENIGFFSASIAANVVNDNPTFQGPRYKGLKTADDFTNALRNGTISFIVDEVPYVKLFVAKHPSEFVIVETESVTNGFGFAFQKGSPLVQKVSREIEKLRRTEKLKAIENWWFQRQTTSATSEDTFHPLTVYTFRGLFMITGVSFAFALIVYLIPWNREQRQVVLKHFHRYVSHRFAREIRPSPTTPNRQNENSVI

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed predominantly in roots and siliques

DOI ID

10.1093/oxfordjournals.molbev.a004165; 10.1038/35048706; 10.1111/tpj.13415; 10.1126/science.292.5521.1486b; 10.1016/j.jmb.2008.06.076

RefSeq

NP_187408.2